July 1982
Volume 23, Issue 1
Articles  |   July 1982
Limbal epithelium in ocular surface wound healing.
Investigative Ophthalmology & Visual Science July 1982, Vol.23, 73-80. doi:https://doi.org/
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      S Kinoshita, T C Kiorpes, J Friend, R A Thoft; Limbal epithelium in ocular surface wound healing.. Invest. Ophthalmol. Vis. Sci. 1982;23(1):73-80. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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The regenerated epithelium derived from limbal epithelium was histologically and biochemically compared with epithelia regenerated from corneal and bulbar conjunctival epithelia. The histologic results indicated that regenerated epithelium of limbal origin increased in thickness with time after healing and showed no goblet cell appearance on the cornea. This suggests that regenerated epithelium from the limbus is more like regenerated epithelium of corneal origin than that of bulbar conjunctival origin. However, the glycogen content and protein pattern profile showed that regenerated epithelium of limbal origin had characteristics intermediate between those of corneal and bulbar conjunctival origin. Thus it is proposed that there are three distinct types of ocular surface epithelia--corneal, bulbar conjunctival, and limbal--and that limbal epithelium behaves differently from corneal and conjunctival epithelia in ocular surface wound healing.


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