January 1984
Volume 25, Issue 1
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Articles  |   January 1984
Retinoblastoma: tissue culture lines and monoclonal antibody studies.
Investigative Ophthalmology & Visual Science January 1984, Vol.25, 30-40. doi:
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      D H Char, I S Wood, K Huhta, N Rand, C T Morita, E L Howes; Retinoblastoma: tissue culture lines and monoclonal antibody studies.. Invest. Ophthalmol. Vis. Sci. 1984;25(1):30-40.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Retinoblastoma patients have cellular and humoral reactivity towards antigens expressed on retinoblastoma cells. We report the ultrastructural, cytogenetic, and immunologic features of four new retinoblastoma derived tissue culture cell lines. Studies with hybridoma produced monoclonal antibodies demonstrate that these lines share antigens with a previously described long-term allogeneic retinoblastoma derived tissue culture cell line, as well as with antigens on fresh retinoblastoma.

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