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A K Harvey, F Roberge, L M Hjelmeland; Chemotaxis of rat retinal glia to growth factors found in repairing wounds.. Invest. Ophthalmol. Vis. Sci. 1987;28(7):1092-1099.
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Retinal glia migrate to sites in the vitreous body and on the inner and outer surfaces of the retina during a wide variety of pathological processes. Using in vitro cultures of rat retinal glia, we have evaluated an extensive list of homogeneous, well-characterized growth factors as chemoattractants for these cells. Humoral growth factors, fibroblast growth factors, extracellular matrix proteins and immune system cytokines all were without activity except for the platelet-derived growth factor (PDGF). Extracts of bovine ocular tissues including vitreous body and retina yielded significant activity.
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