August 1991
Volume 32, Issue 9
Free
Articles  |   August 1991
Cone electroretinographic change during light adaptation in retinitis pigmentosa.
Author Affiliations
  • S Miller
    Berman-Gund Laboratory, Massachusetts Eye & Ear Infirmary, Boston 02114.
  • M A Sandberg
    Berman-Gund Laboratory, Massachusetts Eye & Ear Infirmary, Boston 02114.
Investigative Ophthalmology & Visual Science August 1991, Vol.32, 2536-2541. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      S Miller, M A Sandberg; Cone electroretinographic change during light adaptation in retinitis pigmentosa.. Invest. Ophthalmol. Vis. Sci. 1991;32(9):2536-2541.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Cone electroretinograms (ERGs) to 30-Hz full-field white light were recorded after dark adaptation from 33 patients with retinitis pigmentosa and 8 normal subjects over a period averaging 8.5 min. Most patients and all normal subjects showed increases in amplitude that approached or reached maximum by the end of the recording. Regression analyses revealed that patients with smaller baseline amplitudes tended to show larger and faster increases in relative amplitude than patients with larger baseline amplitudes, whose amplitude changes over time were comparable to those seen in normal subjects. These findings suggest that both the magnitude and kinetics of cone ERG amplitude change to a light-adapting, flickering stimulus are related directly to the level of cone malfunction in retinitis pigmentosa.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×