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M Korth, N X Nguyen, F Horn, P Martus; Scotopic threshold response and scotopic PII in glaucoma.. Invest. Ophthalmol. Vis. Sci. 1994;35(2):619-625.
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PURPOSE: The value of the ERG scotopic threshold response (STR), which is known to originate in the proximal retina and of the near-threshold scotopic PII(B-wave), was studied in glaucoma. METHODS: Full-field single flashes were presented under scotopic conditions in two subject groups, a glaucoma group (n = 30) and a normal control group (n = 35). The intensity level for evoking STR was where the maximum response occurs, whereas the intensity level for evoking scotopic PII was where the response begins to appear. RESULTS: The STR is only slightly reduced in glaucoma (P = 0.046), but scotopic PII is significantly diminished (P < 0.0001). CONCLUSIONS: The relatively intact STR in glaucoma suggests that structures responsible for its generation are less damaged in glaucoma than those responsible for scotopic PII.
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