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Janette Atkinson, Shirley Anker, William Bobier, Oliver Braddick, Kim Durden, Marko Nardini, Peter Watson; Normal Emmetropization in Infants with Spectacle Correction for Hyperopia. Invest. Ophthalmol. Vis. Sci. 2000;41(12):3726-3731.
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purpose. The development of emmetropic refraction is known to be under visual
control. Does partial spectacle correction of infants’ refractive
errors, which has been shown to have beneficial effects in reducing
strabismus and amblyopia, impede emmetropization? The purpose of the
present study was to perform the first longitudinal controlled trial to
investigate this question in human subjects.
methods. Children identified as having significant hyperopia in a population
screening program at age 8 to 9 months were assigned to treated
(partial spectacle correction) or untreated groups. A control group of
infants with no significant refractive errors at screening was also
recruited. Measurements of retinoscopic refraction under cycloplegia
were taken at 4- to 6-month intervals up to the age of 36 months, and
changes in refraction of 148 subjects were analyzed longitudinally.
results. Refractive error decreased toward low hyperopic values between 9 and 36
months in both hyperopic groups. By 36 months, this reduction of
hyperopia showed no overall difference between children who were
treated with partial spectacle correction and those who were not.
Despite the improvement, both hyperopic groups’ mean refractive error
at 36 months remained higher than that of the control group. When
infants in all three groups were considered together, the rate of
reduction of refractive error was, on average, a linear function of the
initial level of hyperopia.
conclusions. The benefits of spectacle correction for infants with hyperopia can be
achieved without impairing the normal developmental regulation of
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