February 1965
Volume 4, Issue 1
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Articles  |   February 1965
Effect of Composition of Medium and of Metabolic Inhibitors on Secretion in vitro by the Ciliary Processes Of The Rabbit Eye
Author Affiliations
  • LENNART BERGGREN
    Departments of Pharmacology and Ophthalmology, University of Uppsala Sweden
Investigative Ophthalmology & Visual Science February 1965, Vol.4, 83-90. doi:
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      LENNART BERGGREN; Effect of Composition of Medium and of Metabolic Inhibitors on Secretion in vitro by the Ciliary Processes Of The Rabbit Eye. Invest. Ophthalmol. Vis. Sci. 1965;4(1):83-90.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A previously described in vitro method of studying secretion by measurements of an optical transverse section of the ciliary processes was used. It ivas found that the mechanism responsible for the secretory pump was specific for sodium ions and discriminated between sodium and lithium. A high concentration of potassium in the medium did not affect the pump. Inhibitors such as cyanide, dinitrophenol, azide, and ouabain, but not monoiodoacetate, inhibited secretion. The similarities between the transport mechanism in other epithelial tissues and in the ciliary processes are discussed.

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