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Effect of Parasympathomimetic and Sympathomimetic Drugs on Secretion in vitro by the Ciliary Processes of the Rabbit Eye. Invest. Ophthalmol. Vis. Sci. 1965;4(1):91-97.
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Secretion was measured by determining differences in the area of an optical transverse section of the ciliary processes. Pilocarpine is an effective inhibitor of secretion in vitro at 10-9M, while acetylcholine, carbachol, and arecoline inhibited only at 10-5M. Physostigmine as ivell as atr opine had an inhibitory effect at 10-7M and epinephrine depressed secretion at 10-4M; a combination of epinephrine and acetazolamide teas not synergistic. The inhibitory effect of epinephrine could be abolished by blocking its metabolic effects by N-isopropyl methoxamine.
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