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Roy de Kinkelder, Jeroen Kalkman, Dirk J. Faber, Olaf Schraa, Pauline H. B. Kok, Frank D. Verbraak, Ton G. van Leeuwen; Heartbeat-Induced Axial Motion Artifacts in Optical Coherence Tomography Measurements of the Retina. Invest. Ophthalmol. Vis. Sci. 2011;52(6):3908-3913. doi: 10.1167/iovs.10-6738.
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© 2017 Association for Research in Vision and Ophthalmology.
To investigate the cause of axial eye motion artifacts that occur in optical coherence tomography (OCT) imaging of the retina. Understanding the cause of these motions can lead to improved OCT image quality and therefore better diagnoses.
Twenty-seven measurements were performed on 5 subjects. Spectral domain OCT images at the macula were collected over periods up to 30 seconds. The axial shift of every average A-scan was calculated with respect to the previous average A-scan by calculating the cross-correlation. The frequency spectrum of the calculated shifts versus time was determined. The heart rate was determined from blood pressure measurements at the finger using an optical blood pressure detector. The fundamental frequency and higher order harmonics of the axial OCT shift were compared with the frequency spectrum of blood pressure data. In addition, simultaneous registration of the movement of the cornea and the retina was performed with a dual reference arm OCT setup, and movements of the head were also analyzed.
A correlation of 0.90 was found between the fundamental frequency in the axial OCT shift and the heart rate. Cornea and retina move simultaneously in the axial direction. The entire head moves with the same amplitude as the retina.
Axial motion artifacts during OCT volume scanning of the retina are caused by movements of the whole head induced by the heartbeat.
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