August 1968
Volume 7, Issue 4
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Articles  |   August 1968
Characterization of the Transport of Neutral Amino Acids by the Calf Lens
Author Affiliations
  • D. BRASSIL
    Department of Ophthalmology, Albeit Einstein College of Medicine of Yeshiva University, New York, N.Y.
  • H. L. KERN
    Department of Ophthalmology, Albeit Einstein College of Medicine of Yeshiva University, New York, N.Y.
Investigative Ophthalmology & Visual Science August 1968, Vol.7, 441-451. doi:
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      D. BRASSIL, H. L. KERN; Characterization of the Transport of Neutral Amino Acids by the Calf Lens. Invest. Ophthalmol. Vis. Sci. 1968;7(4):441-451.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A number of selective sites have been found in the calf lens at which cellular transport of the neutral amino acids takes place. The characterization of two of these, the A-site and the Lsite, agrees with that of Christensen for these sites in other tissues. The existence of a third, site, X, was also demonstrated. The X-site was selective for the small amino acids, glycine and sarcosine, and alanine to a lesser extent. Most of the entry of the neutral amino acids occurred at these sites, with the residual or so-called unsaturable component usually constituting a small proportion of the total cellular uptake.

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