May 1970
Volume 9, Issue 5
Free
Articles  |   May 1970
Dexamethasone Testing in Southwestern Indians
Author Affiliations
  • LOUIS J. ROSENBAUM
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
  • ELLEN ALTON
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
  • BERNARD BECKER
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
Investigative Ophthalmology & Visual Science May 1970, Vol.9, 325-330. doi:
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      LOUIS J. ROSENBAUM, ELLEN ALTON, BERNARD BECKER; Dexamethasone Testing in Southwestern Indians. Invest. Ophthalmol. Vis. Sci. 1970;9(5):325-330.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Indians of the Southwestern United States demonstrated prevalences of primary open-angle glaucoma and responsiveness to topical dexamethasone which were comparable to nonlndian St. Louis populations. In both populations plasma cortisol suppression by oral dexamethasone was decreased in individuals in the group most responsive to topical dexamethasone. Indians demonstrated very high prevalences of phenylthiourea tasters and positive oral glucose tolerance tests but, contrary to the St. Louis populations, these two parameters did not correlate with the topical dexamethasone response.

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