December 1975
Volume 14, Issue 12
Free
Articles  |   December 1975
Origin and development of Bruch's membrane in monkey fetuses: an electron microscopic study.
Investigative Ophthalmology & Visual Science December 1975, Vol.14, 903-916. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Y Takei, V Ozanics; Origin and development of Bruch's membrane in monkey fetuses: an electron microscopic study.. Invest. Ophthalmol. Vis. Sci. 1975;14(12):903-916.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

The appearance of the components of Bruch's membrane in staged monkey fetuses was investigated with the electron microscope. The formation of this structure is closely associated with the morphological and cytological changes of the adjoining tissues. The sequence of events in the primate is as follows: (1) establishment of basal lamina of the pigment epithelium on the twenty-seventh day of gestation (optic cup stage); (2) appearance of some aggregated collagen fibers with nodosities on the thirty-eighth day of gestation; (3) layering of some collagen fibers with striations on the forty-sixth day of gestation; (4) appearance of the first immature elastic fibrils on the forty-ninth day of gestation; and (5) incomplete formation of basal lamina of the choriocapillary endothelium on the fifty-fourth day of gestation. The observations are discussed in relation to published work which has a bearing on Bruch's membrane formation.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×