February 1975
Volume 14, Issue 2
Articles  |   February 1975
Effects of monosodium glutamate on chick embryo retina in culture.
Investigative Ophthalmology & Visual Science February 1975, Vol.14, 114-124. doi:
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      L Reif-Lehrer, J Bergenthal, L Hanninen; Effects of monosodium glutamate on chick embryo retina in culture.. Invest. Ophthalmol. Vis. Sci. 1975;14(2):114-124.

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      © ARVO (1962-2015); The Authors (2016-present)

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Monosodium glutamate added to 12-day chick embryo retinas in culture causes severe morphologic damage to the retina as judged by light microscopic examination. Damage is evident after a few hours with concentrations as low as 0.3 mM. Glutamyltransferase induction is also appreciably inhibited by the amino acid. General protein synthesis and RNA synthesis appear to be less affected.


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