October 1976
Volume 15, Issue 10
Articles  |   October 1976
The effect of tonicity on lens volume.
Investigative Ophthalmology & Visual Science October 1976, Vol.15, 866-869. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J W Patterson, D J Fournier; The effect of tonicity on lens volume.. Invest. Ophthalmol. Vis. Sci. 1976;15(10):866-869.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

Rat lenses incubated in hypotonic medium adapted to the medium by first undergoing osmotic swelling and then returning after 1 to 2 days to their originial volume. Two processes--osmotic swelling and volume regulation--appear to be working simultaneously. The former is indicated by a decrease in the concentration of cell potassium to the expected level and the latter by a limitation of lens volume associated with a decrease in the potassium content of the lens. These findings are consistent with those observed in other types of cells and may be of significance in understanding the etiology of cataracts.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.