December 1977
Volume 16, Issue 12
Free
Articles  |   December 1977
The effect of topical pilocarpine on intraocular pressure and pupil size in the normotensive and glaucomatous beagle.
Investigative Ophthalmology & Visual Science December 1977, Vol.16, 1143-1148. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      R M Gwin, K N Gelatt, G G Gum, R L Peiffer, Jr, L W Williams; The effect of topical pilocarpine on intraocular pressure and pupil size in the normotensive and glaucomatous beagle.. Invest. Ophthalmol. Vis. Sci. 1977;16(12):1143-1148.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Topical 1, 2, and 4 percent pilocarpine were evaluated in the normotensive and glaucomatous beagles, comparing intraocular pressure (IOP), pupillary size, and time. In normotensive beagles pilocarpine produced maximal decreases of 25 percent (5.5 mm. Hg) at 1 percent concentration; 34 percent (7.26 mm. Hg) at 2 percent concentration; and 25 percent (6.9 mm. Hg) at 4 percent concentration. The maximum reductions in IOP after pilocarpine instillation in the glaucomatous beagle were 30 percent (9.1 mm. Hg) at 1 percent concentration; 44 percent (14.92 mm. Hg) at 2 percent concentration; and 31 percent (10.89 mm. Hg) at 4 percent concentration. The glaucomatous beagles responded with a greater reduction of IOP than did the normotensive beagles.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×