October 1978
Volume 17, Issue 10
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Articles  |   October 1978
Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length light.
Investigative Ophthalmology & Visual Science October 1978, Vol.17, 1029-1035. doi:
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      W T Ham, J J Ruffolo, H A Mueller, A M Clarke, M E Moon; Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length light.. Invest. Ophthalmol. Vis. Sci. 1978;17(10):1029-1035.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The photopathology of retinal lesions produced by extended exposure (1000 sec) to low corneal power levels (62 microW) of blue light (441 nm) was investigated by light microscopy in 20 rhesus eyes over an interval ranging from 1 hr to 90 days after exposure. Results indicate a nonthermal type of photochemical lesion originating in the retinal pigment epithelium and leading to a histological response with hypopigmentation which requires 48 hr to appear. This type of lesion helps to explain solar retinitis and eclipse blindness and has significance for aging and degenerative changes in the retina.

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