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D A Witzel, E L Smith, R D Wilson, G D Aguirre; Congenital stationary night blindness: an animal model.. Invest. Ophthalmol. Vis. Sci. 1978;17(8):788-795.
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© ARVO (1962-2015); The Authors (2016-present)
Electroretinographic studies of myctalopic Appaloosa horses demonstrated photopic and scotopic abnormalities similar to those in humans with congenital stationary night blindness (CSNB) of the Schubert-Bornschein type. The phototopic abnormalities consisted of reduced b-wave amplitudes and slower than normal b-wave implict time. The dark-adapted ERG's consisted of a simple negative potential; the scotopic b-wave was nonrecordable. However, a normal c-wave was present in the dark-adapted response. Histologic studies demonstrated no structural abnormalities that could explain the functional defect.
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