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D A Witzel, E L Smith, R D Wilson, G D Aguirre; Congenital stationary night blindness: an animal model.. Invest. Ophthalmol. Vis. Sci. 1978;17(8):788-795.
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© 2016 Association for Research in Vision and Ophthalmology.
Electroretinographic studies of myctalopic Appaloosa horses demonstrated photopic and scotopic abnormalities similar to those in humans with congenital stationary night blindness (CSNB) of the Schubert-Bornschein type. The phototopic abnormalities consisted of reduced b-wave amplitudes and slower than normal b-wave implict time. The dark-adapted ERG's consisted of a simple negative potential; the scotopic b-wave was nonrecordable. However, a normal c-wave was present in the dark-adapted response. Histologic studies demonstrated no structural abnormalities that could explain the functional defect.
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