June 1987
Volume 28, Issue 6
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Articles  |   June 1987
Tubocurarine chloride inhibits rod outer segment shedding in the frog retina.
Investigative Ophthalmology & Visual Science June 1987, Vol.28, 1030-1032. doi:
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      W C Gordon, M E Keith; Tubocurarine chloride inhibits rod outer segment shedding in the frog retina.. Invest. Ophthalmol. Vis. Sci. 1987;28(6):1030-1032.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The cholinergic postsynaptic neuromuscular blocker, tubocurarine chloride (curare), attenuates the rod shedding response of the frog in a dose-dependent manner. Injections of curare into the dorsal lymph sacs or intraocularly into the vitreous of the eye produced similar results. Intraocular injections of Ringer solution of varying quantities of 0.9% NaCl (the carrier solution of the commercially prepared curare), had no adverse effect on the shedding response. Additionally, injections of curare into one eye had no effect on the rod shedding rate of the other eye.

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