September 1988
Volume 29, Issue 9
Free
Articles  |   September 1988
Developmental changes in proteoglycans of rabbit corneal stroma.
Author Affiliations
  • J D Gregory
    Rockefeller University, New York, NY 10021.
  • S P Damle
    Rockefeller University, New York, NY 10021.
  • H I Covington
    Rockefeller University, New York, NY 10021.
  • C Cintron
    Rockefeller University, New York, NY 10021.
Investigative Ophthalmology & Visual Science September 1988, Vol.29, 1413-1417. doi:
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    • Get Citation

      J D Gregory, S P Damle, H I Covington, C Cintron; Developmental changes in proteoglycans of rabbit corneal stroma.. Invest. Ophthalmol. Vis. Sci. 1988;29(9):1413-1417.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Proteoglycans have been extracted from rabbit corneal stromas at developmental stages from fetal to adult. Ion exchange fractionation and gel chromatography show that proteodermatan sulfates decrease in sulfation and relative amount and proteokeratan sulfates increase in sulfation and relative amount during development. There are small increases in size of all of the proteoglycans up to 2 weeks after birth, and the final adult composition is achieved by 8 weeks.

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