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Esther G. González, Luminita Tarita-Nistor, Efrem D. Mandelcorn, Mark Mandelcorn, Martin J. Steinbach; Fixation Control before and after Treatment for Neovascular Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2011;52(7):4208-4213. doi: 10.1167/iovs.10-7026.
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We studied changes in visual acuity (VA), fixation stability, and location of the preferred retinal locus (PRL) after treatment for unilateral neovascular age-related macular degeneration (AMD) for previously untreated eyes. Concomitant changes in fixation stability, PRL, and VA in the untreated fellow eye were also analyzed.
Pre- and posttreatment tests of visual acuity, fixation stability, and PRL location in both the treated and the untreated eyes were performed on 13 patients undergoing three monthly intravitreal injections of ranibizumab in one eye.
For the treated eyes there were improvements in VA and fixation stability but no changes in the location of the PRL. No significant changes in any of the three variables were found in the untreated eye.
For previously untreated eyes, the improvement in visual acuity after intravitreal ranibizumab injections was accompanied by improvement in fixation stability.
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