June 2011
Volume 52, Issue 7
Free
Letters to the Editor  |   June 2011
Author Response: Incorrect Citation
Author Affiliations & Notes
  • Hua Yang
    Department of Ophthalmology, Emory University, Atlanta, Georgia.
  • Hans E. Grossniklaus
    Department of Ophthalmology, Emory University, Atlanta, Georgia.
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4368. doi:10.1167/iovs.11-7341
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    • Get Citation

      Hua Yang, Hans E. Grossniklaus; Author Response: Incorrect Citation. Invest. Ophthalmol. Vis. Sci. 2011;52(7):4368. doi: 10.1167/iovs.11-7341.

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      © ARVO (1962-2015); The Authors (2016-present)

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  • Supplements
We 1 thank David Bates for pointing out that Hua et al. 2 showed that recombinant human VEGF165b inhibits experimental murine choroidal neovascularization, but did not show an effect of bevacizumab on mouse models of choroidal neovascularization. We do note that bevacizumab has an effect on reducing corneal neovascularization in the mouse eye. 3,4 It appears that the route and timing of administration play a role in this effect. In our model, intracameral bevacizumab reduced the number of hepatic micrometastases from ocular melanoma. We cannot exclude that this may have been due to selective inhibition of intraocular melanoma cells rather than an antiangiogenic effect. 
References
Yang H Jager MJ Grossniklaus HE . Author response: Bevacizumab suppression of establishment of micrometastases in experimental ocular melanoma. Invest Ophthalmol Vis Sci. 2010;51:6906–6907. [CrossRef] [PubMed]
Hua J Spee C Kase S . Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2010;51:4282–4288. [CrossRef] [PubMed]
Avisar I Weinberger D Kremer I . Effect of subconjunctival and intraocular bevacizumab injections on corneal neovascularization in a mouse model. Curr Eye Res. 2010;35:108–115. [CrossRef] [PubMed]
Dratviman-Storobinsky O Avraham Lubin BR Hasanreisoglu M Goldenberg-Cohen N . Effect of subconjunctival and intraocular bevacizumab injection on angiogenic gene expression levels in a mouse model of corneal neovascularization. Mol Vis. 2009;15:2326–2338. [PubMed]
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