January 1970
Volume 9, Issue 1
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Articles  |   January 1970
The Measurement of Pseudofacility and True Facility by Constant Pressure Perfusion in the Normal Rhesus Monkey Eye
Author Affiliations
  • RICHARD F. BRUBAKER
    Howe Laboratory of Ophthalmology, Harvard Medical School, Boston, Mass., and the Ophthalmology Branch, National Institute of Neurological Diseases and Stroke, National Institutes of Health, United States Department of Health, Education, and Welfare, Bethesda, Md.
Investigative Ophthalmology & Visual Science January 1970, Vol.9, 42-52. doi:
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      RICHARD F. BRUBAKER; The Measurement of Pseudofacility and True Facility by Constant Pressure Perfusion in the Normal Rhesus Monkey Eye. Invest. Ophthalmol. Vis. Sci. 1970;9(1):42-52.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Facility of bulk aqueous humor outflow via conventional channels, true facility, and pressure sensitive suppression of aqueous humor inflow, pseudofacility, were measured by constant pressure perfusion in 24 eyes of 12 rhesus monkeys. True facility ivas found to have a mean value of 0.55µL min-1 mm. Hg-1 and pseudofacility was found to have a mean value of 0.12 µL min-1mm. Hg-1. This figure is in general agreement with other published values for pseudofacility in a variety of species. It is concluded that suppression of formation of aqueous humor by elevation of intraocular pressure exerts a small but significant stabilizing effect on the intraocular pressure in the normal eye. It is speculated that pseudofacility may have a much greater relative influence on intraocular dynamics in disease states in which the conventional outflow pathways are pathologically occluded.

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