October 1970
Volume 9, Issue 10
Free
Articles  |   October 1970
Changes in Lens Fatty Acid Composition During Galactose Cataract Formation
Author Affiliations
  • HAROLD HATCHER
    Division of Ophthalmology, Department of Surgery, Vanderbilt University School of Medicine Nashville, Tenn.
  • J. Stevens ANDREWS
    Division of Ophthalmology, Department of Surgery, Vanderbilt University School of Medicine Nashville, Tenn.
Investigative Ophthalmology & Visual Science October 1970, Vol.9, 801-806. doi:
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      HAROLD HATCHER, J. Stevens ANDREWS; Changes in Lens Fatty Acid Composition During Galactose Cataract Formation. Invest. Ophthalmol. Vis. Sci. 1970;9(10):801-806.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A high level of fat in the diet of galactose-fed weanling rats has been reportedto delay the onset of mature cataracts. Groups of rats fed lab chow, sucrose, and galactose-high-fat diets had essentially similar total fatty acid compositions in their lenses, but rats receiving a low level of corn oil in a galactose diet were observed to have differences in the long-chain unsaturated fatty acids when compared to the control groups. This observation suggests that the lenses of unsupplemented galactose-fed rats have a relative deficiency of certain longchain unsaturated fatty acidsand might account for the difference in the time of mature cataract formation which has been observed with the two diets.

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