April 1965
Volume 4, Issue 2
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Articles  |   April 1965
The Effect of Death on Outflow Resistance in Normal and Sympathectomized Rabbit Eyes
Author Affiliations
  • ERNST H. BÁRÁNY
    Department of Pharmacology, University of Uppsala, Uppsala, Sweden
  • HANS B. GASSMANN
    Department of Pharmacology, University of Uppsala, Uppsala, Sweden
Investigative Ophthalmology & Visual Science April 1965, Vol.4, 206-210. doi:
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      ERNST H. BÁRÁNY, HANS B. GASSMANN; The Effect of Death on Outflow Resistance in Normal and Sympathectomized Rabbit Eyes. Invest. Ophthalmol. Vis. Sci. 1965;4(2):206-210.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The resistance drop Δ R caused after 25 hours by superior cervical ganglionectomy in a group of 19 rabbits was linearly related to the resistance of the normal eye R, by the equation Δ R = (0.73 ± 0.04) (Rc - 1.56) mm. Hg/µl x minute-1. Ten to 30 minutes after death by cardiotomy, resistance of the normal eye had decreased by amounts depending on the resistance in life. The relation between resistance drop Δ R and resistance during life R1 was described by Δ R = (0.84 ± 0.07) (R1 - 4.50) mm. Hg/µl x minute-. Resistance of eyes ganglionectomized 25 hours earlier did not change considerably. Even after death, resistance was lower on the ganglionectomized side. The data indicate that the ganglionectomy effect does not depend on blood circulation and that the resistance component which decreases after ganglionectomy is the same as that which is affected by interruption of the systemic blood circulation.

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