June 1965
Volume 4, Issue 3
Free
Articles  |   June 1965
Ocular Responses to Autonomic Drugs in Familial Dysautonomia
Author Affiliations
  • ALFRED A. SMITH
    Departments of Psychiatry, Pediatrics, and Ophthalmology, New York University Medical Center, New York, N. Y.
  • JOSEPH DANCIS
    Departments of Psychiatry, Pediatrics, and Ophthalmology, New York University Medical Center, New York, N. Y.
  • GOODWIN BREININ
    Departments of Psychiatry, Pediatrics, and Ophthalmology, New York University Medical Center, New York, N. Y.
Investigative Ophthalmology & Visual Science June 1965, Vol.4, 358-361. doi:
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    • Get Citation

      ALFRED A. SMITH, JOSEPH DANCIS, GOODWIN BREININ; Ocular Responses to Autonomic Drugs in Familial Dysautonomia. Invest. Ophthalmol. Vis. Sci. 1965;4(3):358-361.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Familial dysautonomia presents a tetrad of symptoms referable to the eye which are quite regularly present and which, in association, are distinctive and virtually diagnostic. These are alacrima, corneal hypesthesia or anesthesia, exodeviation, and pupillary constriction following the local administration of 2.5 per cent methacholine. These manifestations appear to be related to other symptoms of the disease.

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