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Miguel A Zapata, Ahmad Zaben, Jose Garcia-Arumi; Correlations between functional data using microperimetry and anatomical parameters in high myopia.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1141.
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To investigate choroidal and macular thickness in high myopic patients and their correlation with microperimetry, age and spherical equivalent.
Transversal study. We included patients with high myopia (over -6DD). Patients with other macular diseases or without central fixation were excluded. We studied visual acuity, spherical equivalent, retinal sensitivity with macular perimeter MAIA TM, choroidal and macular thickness were studied with Topcon 3D.
We included 96 eyes with high myopia, spherical equivalent were from -6DD to -20DD (average -8,74 ±2,73). Age average was (38,88 ±13,15). Macular thickness was 199,42.00±25,06 μm. Choroidal thickness 159,00±50,57 μm. Macular sensitivity did not correlate with macular thickness (r = -0,174, p = 0.101). There was a correlation between microperimetry and choroidal thickness (r = 0,306; p = 0,004). We found also correlation between sensitivity and visual acuity (r = 0,431, p = 0.000), and spherical equivalent (r = -0,306, p = 0.003). Macular thickness was not related to visual acuity or age. Choroidal thickness was directly related with microperimetry and visual acuity, there was a negative correlation with spherical value and age.
This study confirms the relation between functional and anatomical findings in high myopic patients. Macular sensitivity decreases with age and also with the spherical equivalent. Choroidal thickness seems to be the anatomical factor most related to sensitivity in microperimetry. Higher choroidal thickness correlates with better visual acuity and macular sensitivity. Choroidal thickness decreases also with spherical value and age.
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