April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
A Technique for Ocular Surface Reconstruction with Keratolimbal Allograft for Recurrent Symblepharon
Author Affiliations & Notes
  • Nancy Lee
    Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA
  • Marjan Farid
    Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA
  • Footnotes
    Commercial Relationships Nancy Lee, None; Marjan Farid, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1486. doi:
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      Nancy Lee, Marjan Farid; A Technique for Ocular Surface Reconstruction with Keratolimbal Allograft for Recurrent Symblepharon. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1486.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To describe a technique for recurrent symblepharon repair with ocular surface reconstruction using keratolimbal allograft tissue.

Methods: Three eyes of three patients with recurrent symblepharon causing restrictive diplopia in primary gaze were treated. Following meticulous symblephara lysis and scar tissue removal, keratolimbal allograft (KLAL) tissue was used to reconstruct the ocular surface and provide a spacer to prevent recurrent scarring. The primary outcome measures are symblepharon recurrence and diplopia in primary position. Secondary outcome measures include diplopia in cardinal directions of gaze.

Results: All three eyes were free of symblepharon recurrence in areas reconstructed with KLAL sections. Mild recurrence of adhesions occurred only up to the edge of the KLAL graft, without violating the donor tissue. The diplopia in primary gaze was resolved and maintained in all cases with only mild recurrent diplopia in extreme lateral gaze.

Conclusions: Ocular surface reconstruction with KLAL is an effective procedure in patients with recurrent symblepharon. Donor KLAL is a robust tissue alternative to traditional amniotic membrane or conjunctival autografts for the treatment of recurrent symblepharon.

Keywords: 741 transplantation • 479 cornea: clinical science  
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