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Brian C Toy, Edward E Manche; Vector analysis of compound myopic astigmatism comparing wavefront-guided and wavefront-optimized excimer platforms. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1518.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the astigmatic outcomes of laser in situ keratomileusis (LASIK) with a single excimer laser platform using either wavefront-guided (WFG) and a wavefront-optimized (WFO) modes.
Seventy-two eyes of 36 patients underwent LASIK for compound myopic astigmatism with the Alcon Wavelight Allegretto Eye-Q 400 laser platform. One eye underwent WFG-LASIK, and the contralateral eye underwent WFO-LASIK. Preoperative and postoperative assessments were performed and included manifest refraction, vector analysis, topographic analysis, and wavefront aberrometry analysis. Eyes were stratified for subgroup analysis based on preoperative manifest astigmatism: 0.25-1, 1.25-2.25, and 2.5-3.5 diopters. Statistics were calculated using t-tests.
Preoperatively, mean spherical equivalent (SE) was -4.0±1.7 vs -3.9±1. diopters(D) (p=0.67), and mean cylindrical error(CE) was 0.7±0.5 vs 0.8±0.8D (p=0.47) in the Alcon-WFG and Alcon-WFO groups, respectively. At postoperative month 12, mean SE was -0.2 ±0.3 vs -0.3±0.3D (p=0.03), and mean CE was 0.2±0.2 vs 0.1±0.2D (p=0.46), respectively. Alpins vector analyses for the Alcon-WFG and Alcon-WFO groups, respectively, were: surgically-induced-astigmatism (0.8±0.6 vs 0.8±0.8D, p=0.94), error-magnitude (0.1±0.2 vs 0.1±0.2D, p=0.77), error-angle (10±37° vs 19±44°, p=0.4), correction-index (1.1±0.3 vs 1±0.3, p=0.1), success-index (0.2±0.3 vs 0.2±0.4, p=0.45), and flattening-index (0.8±0.5 vs 0.9±0.8, p=0.19). Subgroup analysis by preoperative astigmatism showed no significant differences.
Minimal difference in outcomes between Alcon-WFG and Alcon-WFO platforms based on objective Alpins analysis of astigmatism.
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