April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Prevalence of Lens Opacities in Adult Chinese Americans: The Chinese American Eye Study (CHES)
Author Affiliations & Notes
  • Mina Torres
    University of Illinois at Chicago, Los Angeles, CA
  • Jie Sun
    University of Illinois at Chicago, Los Angeles, CA
  • Shuang Wu
    University of Illinois at Chicago, Los Angeles, CA
  • Chunyi Hsu
    University of Illinois at Chicago, Los Angeles, CA
  • Roberta McKean-Cowdin
    University of Southern California, Los Angeles, CA
  • Stanley Paul Azen
    University of Southern California, Los Angeles, CA
  • Rohit Varma
    University of Illinois at Chicago, Los Angeles, CA
  • Footnotes
    Commercial Relationships Mina Torres, None; Jie Sun, None; Shuang Wu, None; Chunyi Hsu, None; Roberta McKean-Cowdin, None; Stanley Azen, None; Rohit Varma, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1570. doi:
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      Mina Torres, Jie Sun, Shuang Wu, Chunyi Hsu, Roberta McKean-Cowdin, Stanley Paul Azen, Rohit Varma, ; Prevalence of Lens Opacities in Adult Chinese Americans: The Chinese American Eye Study (CHES). Invest. Ophthalmol. Vis. Sci. 2014;55(13):1570.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To provide estimates of age- and gender-specific prevalence of posterior nuclear, cortical and posterior subcapsular (PSC) lens opacities in a population-based sample of Chinese-American adults of 50 years and older.

Methods: All participants underwent a detailed home interview and a comprehensive clinical examination that included an assessment of the presence of and severity of lens opacification, using the slit lamp-based Lens Opacities ClassificationSystem II (LOCS II). All lens changes (including pseudophakia/aphakia), any nuclear, PSC, and cortical opacities, and nuclear only, PSC-only, and cortical-only opacities were evaluated. Frequency distributions and chi-square test analyses were used to determine the age- and gender-specific prevalence for each opacity type.

Results: Of the 4,582 who completed the ophthalmic examination 4234 had LOCS II grading. Of these 4234 participants, 7 (0.2%) had PSC-only opacities, 927 (21.9%) had nuclear-only opacities, 386(9.1%) had cortical-only opacities, and 531 (12.5%) had mixed-type opacities. The prevalence of all lens changes (48.0%) increased with older age (P<0.0001). Of all participants with mixed opacities, 126 (23.7%) had monocular visual impairment and 50 (9.4%) had binocular impairment. Four hundred fifty four (9.9%) individuals had undergone cataract extraction in at least one eye.

Conclusions: Our data provide the first population-based estimates of prevalence and severity of lens opacities in Chinese Americans. Nuclear opacities were the most common type. Chinese Americans have higher age-specific prevalence of nuclear opacities compared with Non-Hispanic Whites, Afro-Caribbeans and Latinos.

Keywords: 445 cataract  
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