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Mariam Fawzy, Jessica Taibl, Jessica Blair, Samir I Sayegh; Interchangeability of two spectral domain-optical coherence tomography instruments in diabetic and non-diabetic patients. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1622.
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To compare retinal thickness and volume in diabetic patients by different SD-OCT devices and assess the possibility of interchanging the devices between sessions as a means of optimizing flow in a busy retina clinic and expanding access to primary care diabetic screening.
This is a retrospective observational study in a clinic-based setting. 91 eyes were imaged by two different SD-OCT RTVue (IVue Version 2.6, 2012), and Spectralis Heidelberg in the same clinic visit from 2011-2013. A control group of 20 eyes was assigned to this study. Pathological eyes included Diabetic macular edema, PDR, BDR, CSME, Wet and dry AMD, ERM and glaucoma. Patients were divided into 3 different groups, control group (healthy eyes), Diabetic group (diabetic changes in the eye; DME, BDR, PDR) and non-diabetic group (non-diabetic changes in the eye; AMD,ERM,Gluacoma). In the Heidelberg measurements, the mean values were displayed using the ETDRS scale.
26 eyes in the diabetic group from 16 patients (mean age 59+\-14) with diabetes mellitus type 1 and type 2 for average of 13+\-11 years both tested by RTvue and Heidelberg in the same visit revealed mean measurement for retinal thickness of 292+/- 45 um while mean retinal thickness taken by the Spectralis was 315+/- 47um, giving a mean difference of 23 um between the two devices. On the other hand, in the non-diabetic group, 27 eyes from 15 patients (mean age 78+\-12) were assigned and measured. The mean retinal thickness was 285+/-36um by RTvue, and 307+/-37um by the Heidleberg Spectralis, demonstrating a mean difference of 22um. Control eyes showed similarly consistent differences.
The results on both diseased patients and controls and the introduction of an appropriate correction factor indicate that it is possible to use the specific SD-OCT devices in “dual mode” and obtain results consistent with excellent clinical management of patients with retinal pathologies as well as perform primary care diabetic screening.
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