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Ji Hye Jang, Jin Sung Park; Choroidal Morphology in Myopic Choroidal Neovascularization and Surrounding Area Measured by SD-OCT. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1815.
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To compare the choroidal morphology in myopic choroidal neovascularization (CNV) area and that in surrounding area of CNV using spectral domain optical coherence tomography (SD-OCT).
The retrospective study consisted of 19 patients who have myopic CNV lesion in one eye. Fellow eyes were also recruited as control group. All of these eyes were assessed the choroidal thickness and large choroidal vessel size by SD-OCT. Eyes involving myopic CNV were divided into 2 groups; a neovascular lesion and surrounding area which was 250µm apart from CNV as group 1 and group 2, respectively. Subfoveal lesion of fellow eyes was defined group 3.
The choroidal thickness was 80.00 ± 68.31 µm in group 1, 63.44 ± 67.75 µm in group 2, 71.11 ± 65.69 µm in group 3. The choroidal thickness in group 1 was significantly greatest, that in group 2 was significantly thinnest in three groups (P=0.002, ANOVA test). The size of large choroidal vessel was 57.47 ± 39.78 µm in group 1, 40.45 ± 34.69 µm in group 2, 45.63 ± 37.00 um in group 3. The size of large choroidal vessel in group 1 was significantly greatest, that in group 2 was significantly thinnest in three groups (P=0.001, ANOVA test).
Choroidal thickness and large choroidal vessel size in center of CNV were greater than those in near the CNV. The results suggest that although choroidal new vessels are originated from the thinned choroid, hemodynamic activities of the choroid are increased in center of CNV, focally.
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