April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
The influence of retinal oxygenation on the clinical outcomes in eyes with epiretinal membrane after successful vitrectomy
Author Affiliations & Notes
  • Guenther Weigert
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Robert A Blum
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Stefan Sacu
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Michael Georgopoulos
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Stefan Palkovits
    Department of Clinical Phamacology, Medical University of Vienna, Vienna, Austria
  • Sandra Rezar
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Katharina Eibenberger
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Leopold Schmetterer
    Department of Clinical Phamacology, Medical University of Vienna, Vienna, Austria
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
  • Ursula Schmidt-Erfurth
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
  • Footnotes
    Commercial Relationships Guenther Weigert, None; Robert Blum, None; Stefan Sacu, Allergan (C), Bayer (C), Novartis (C); Michael Georgopoulos, None; Stefan Palkovits, None; Sandra Rezar, None; Katharina Eibenberger, None; Leopold Schmetterer, None; Ursula Schmidt-Erfurth, Alcon (C), Bayer (C), Böhringer (C), Novartis (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 2320. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Guenther Weigert, Robert A Blum, Stefan Sacu, Michael Georgopoulos, Stefan Palkovits, Sandra Rezar, Katharina Eibenberger, Leopold Schmetterer, Ursula Schmidt-Erfurth, ; The influence of retinal oxygenation on the clinical outcomes in eyes with epiretinal membrane after successful vitrectomy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2320.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: In the present study patients with epiretinal membrane underwent 23G vitrectomy and ICG membrane peeling. Little information is available about the effects of this treatment on retinal oxygenation. Hence, we set out to investigate the effects of vitrectomy on retinal oxygenation in patients with epiretinal membrane.

Methods: In this unmasked, prospective study, patients with macular edema as a result of epiretinal membrane scheduled to undergo vitrectomy without endotamponade, were included. The main outcome measure was oxygenation of the retinal vessels. The measurement of oxygenation in retinal vessels and retinal vessel diameters was performed with the Retinal Vessel Analyzer at baseline, then at day 1, day 7, week 4, week 12, and month 6 after surgery. At each follow-up visit, a high-definition OCT examination and ETDRS visual acuity were also performed.

Results: Retinal venous diameter increased significantly at the first follow-up examination. There was no significant change in oxygen saturation in retinal arteries. After an increase at day 1, retinal oxygen saturation in retinal veins decreased significantly at the 6 months follow-up visit versus baseline. Visual acuity tended to increase after 6 months and central retinal thickness was decreased after 6 months as expected.

Conclusions: Vitrectomy for epiretinal membrane may show beneficial short-term effects on retinal oxygenation. In eyes with macular edema due to other pathologies, vitrectomy may be performed as an additional treatment modality. Further studies evaluating whether these effects are associated with changes in long-term visual acuity are warranted.

Keywords: 635 oxygen • 688 retina • 762 vitreoretinal surgery  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×