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Yu Cheol Kim, Kyung Tae Kang, Dong Cheol Lee, Kwang-Soo Kim, Ealmaan Kim, Changyoung Lee; Retinal Fluorescein Angiographic Findings in Cerebral Aneurysm Patients. Invest. Ophthalmol. Vis. Sci. 2014;55(13):256.
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To evaluate retinal fluorescein angiographic findings in patient with cerebral aneurysm compare to those in patients with epiretinal membrane.
A total of 54 patients with previously diagnosed cerebral aneurysm were referred from neurosurgical department. All patients underwent ophthalmologic evaluation to exclude other ophthalmologic disorder and had fluorescein angiography to identify whether retinal macroaneurysm existed. Furthermore, presence of drusen, macular degeneration, cotton wool spot, hard exudates, retinal hemorrhage, arteriolar attenuation, A-V crossing signs and arm to retina time, arteriovenous transit time were evaluated. To compare the result of cerebral aneurysm patients, the FAG finding of unaffected eye in 28 epiretinal membrane patients was utilized.
Mean age in cerebral aneurysm group was 60.98 year compare to 61.32 year in epiretinal membrane group(p=0.85). The prevalence of hypertension and diabetic mellitus was similar in two groups(p=0.63, 0.35, respectively). No case with retinal macroaneurysm was found in both groups. Presence of drusen, macular degeneration, CWs or HEs, arteriolar attenuation, arteriovenous crossing sign was not significantly different in two groups. Presence of retinal hemorrhage found in 3.70% in cerebral aneurysm group and 17.86% in epiretinal membrane group(p=0.04). Mean arm to retina time in cerebral aneurysm group was 18.62 secs and 18.96 in epiretinal membrane group(p=0.52). Mean arteriovenous transit time in cerebral aneurysm group was 10.76 secs and 12.30 in epiretinal membrane group(p=0.14).
The patients with cerebral aneurysm are suggested not to have more chance of retinal macroaneurysm compare to epiretinal membrane patients. Chance of retinal hemorrhage in cerebral aneurysm is considered to lower than that of epiretinal patients.
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