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Atsushi Hayashi, Tomoko Nakamura, Mitsuya Otsuka, Akio Miyakoshi, Toshihiko Oiwake, Tomoko Ueda; Observation of microcystic changes in the inner retina with adaptive optics fundus camera. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2608.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To observe microcystic changes in the inner retina at the macula in the eye of optic neuritis and the eye after the epiretinal membrane surgery with an adaptive optics (AO) fundus camera and to examine correlations to the optical coherence tomography (OCT) images.
A case of optic neuritis with normal tension glaucoma (NTG) and a case of epiretinal membrane were treated at Toyama University Hospital. The case of optic neuritis with NTG was treated with pulse therapy of corticosteroid and the case with epiretinal membrane was treated with a vitrectomy and inner limiting membrane peeling. Microcystic changes in the inner nuclear layer (INL) at the macula of both cases were detected in the OCT images. The areas with microcystic changes detected by OCT were observed using an AO fundus camera (rtx1, Imagine Eyes, France).
The OCT images showed microcystic spaces in the INL in the area with nerve fiber bundle defect in the eye of optic neuritis and NTG. The other eye after the surgery for epiretinal membrane showed similar microcystic spaces in the INL in the area with dissociated optic nerve fiber layer. The AO images revealed the same scaly appearance at the surface of the retina with microcystic changes in the INL. The visual acuity of both cases was 1.0.
The AO images revealed a new and peculiar scaly appearance of the retinal surface, which corresponded with microcystic changes in the INL detected by OCT. AO funduc camera may be useful to observe not only cone photoreceptors but also changes in the inner retina.
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