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Jing Jing Feng, Christina Giannikas, Carolyn Shih, John Seedor, Tatyana Milman, Ira J Udell; Not-So-Benign Scleral Plaques: A Case Series. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3144.
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To investigate the clinical course, management, and outcomes of patients with inflamed senile scleral plaques (SSP).
Retrospective chart review of cases of inflamed SSP with progressive scleromalacia. Histopathology of surgical specimens was examined.
2 patients had non-rheumatic autoimmune sclerouveitis, 1 had infectious bacterial keratoscleritis, 1 had severe ocular surface disease, and 1 had giant papillary conjunctivitis. 4/5 patients required plaque excision to stabilize the sclera, 3/4 surgical specimens revealed an inflammatory cellular infiltrate, and 3/4 patients stabilized following surgery.
Inflamed senile scleral plaques may not have a benign course. In patients with autoimmune, infectious, or ocular surface disease, senile scleral plaques may serve as loci of progressive scleromalacia and require surgical intervention for definitive management.
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