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Ahmad Alali, Samir Jabbour, Hady Saheb, Marc Mydlarski; Retrospective review of surgical outcome with iStent surgery. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3181.
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To evaluate the postoperative outcomes of the trabecular bypass micro-stent (iStent) in patients with glaucoma in a Canadian academic center.
A retrospective interventional case series involving 27 eyes that underwent iStent implantation alone or iStent implantation with concurrent cataract surgery. Both primary and secondary glaucoma cases were included. Patients were assessed preoperatively and postoperatively on day 1 and 7 and months 1, 3,and 6. Examinations included intraocular pressure (IOP), visual acuity, number of glaucoma medications and procedure-related complications.
The mean age of the patients was 74.2 +/- 8.9 (range 61-93). The mean baseline IOP was 18.6 +/- 4.5 (range 10-29) and was decreased to 17.8 +/- 5.6 (P >0.05) at 1 month, to 13 +/- 4.7 at 3 months (P <0.05), and to 13.3 +/- 1.7 (P <0.05) at 6 months. The mean number of glaucoma medications at baseline was 2.6 +/- 0.9 (range 1-4) and was reduced to 1.6 +/- 1.3 at 1 month (P <0.05), 1.7 +/- 1.5 at 3 months (P < 0.05) and 2.25 + 1.5 at 6 months (P >0.05). Postoperative adverse events included IOP spike (raise in IOP > 10mmHg from pre-op baseline) in 13 eyes, mild hyphema in 1 eye, and blockage of the iStent in 3 eyes. Three patients required subsequent glaucoma surgery.
Combined iStent implantation and cataract surgery lead to a significant reduction in IOP and medication use in a Canadian academic center.
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