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Ajay Pillai, Sunil Shah, Raquel Gil Cazorla, Keith H Edwards, Harvey Siy Uy, ; Effects of Intralenticular Photodisruption Without Capsulotomy on Post-operative Intraocular Pressure. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3761.
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To ascertain the possible effects of an laser-assisted intralenticular accommodation restoration treatment on post-operative intraocular pressure.
80 eyes of 80 patients underwent intercapsular photodisruption to assess feasibility of laser-assised lenticular accommodation restoration at the Asian Eye Institute (Makati City, Philippines). Each patient's intraocular pressure (IOP) was measured with a Tonopen (Reichert, Clevelent, OH) at the pre-operative visit, 5 minutes before the procedure, 5 minutes post-procedure, and at the 1 day, 1 week, 2 weeks, and 1 month post-operative visits. Pre-operative IOP was then compared to IOP at each post-operative instance.
Average (SD) measurements for IOP at the 1 day pre-op, 5 mins pre-op, 5 mins post-op, 1 day, 1 week, and 1 month post-op visits were 15.06 (3.41), 17.75 (4.56), 20.49 (8.81), 13.93 (2.89), 15.55 (3.28), 14.26 (3.44), and 15.18 (3.55), respectively. Change (SD, p-value) in IOP 5 mins post-op compared to 5 mins pre-op was +2.71 (7.91, p=0.003). Change in IOP (SD, p-value) at 1 day, 1 week, 2 weeks, and 1 month compared to the pre-operative visit were -1.14 (3.81, p=0.009), -0.68 (5.57, p>0.5), -1.88 (5.59, p>0.5), and -0.45 (4.65, p>0.5).
Intralenticular photodisruption without capsulotomy can cause a minimal and transient elevation of IOP immediately following the procedure. No long term effects on IOP are apparent from this preliminary study.
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