April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Effects of visual noise on binocular summation in strabismic patients without amblyopia
Author Affiliations & Notes
  • Patrick J Lee
    DGSOM UCLA, Los Angeles, CA
  • Federico G Velez
    JSEI- UCLA, los angeles, CA
  • Joseph L Demer
    JSEI- UCLA, los angeles, CA
  • Stacy Pineles
    JSEI- UCLA, los angeles, CA
  • Footnotes
    Commercial Relationships Patrick Lee, None; Federico Velez, None; Joseph Demer, None; Stacy Pineles, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4087. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Patrick J Lee, Federico G Velez, Joseph L Demer, Stacy Pineles; Effects of visual noise on binocular summation in strabismic patients without amblyopia. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4087.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose
 

Patients with strabismus often complain of difficulty navigating through visually stimulating environments without clear explanation for this symptom. Binocular summation (BiS), defined as the superiority of binocular over monocular viewing on visual threshold tasks, is decreased in conditions that cause large interocular differences in visual acuity, but is not well studied in strabismic populations without amblyopia. We hypothesized that strabismus may lead to decreased BiS for tasks related to discrimination within increased background complexity. The goal of this study was to test the extent of BiS in strabismic patients during discrimination of a luminance target disk embedded in visual noise.

 
Methods
 

Ten exotropic, ten esotropic, and thirteen age-matched control subjects participated. Performance of a task detecting a luminance-target was measured 0, 10 and 20 μdeg2 of visual noise for binocular and monocular conditions. BiS was calculated as the ratio of binocular contrast sensitivity to monocular contrast sensitivity for the target embedded in noise.

 
Results
 

Strabismic patients had lower BiS values than controls, with a significant decrease on linear regression in strabismic patients at 20 μdeg2 of noise (p=0.05), with a trend towards significance at 10 μdeg2 of noise (p=0.07). Strabismic patients showed a mean binocular inhibition (summation ratio<1) at both noise levels.

 
Conclusions
 

Our findings support our hypothesis that strabismus can lead to decreased BiS and even binocular inhibition. Despite literature showing enhanced BiS in visually demanding situations such as high levels of visual noise or low contrast, BiS was not significantly affected by visual noise in either group.

 
 
Multiple linear regression model of BiS scores with interocular difference and strabismus vs. control status as co-variates. Strabismus was found to be significantly associated with a decrease in BiS at all three noise levels.
 
Multiple linear regression model of BiS scores with interocular difference and strabismus vs. control status as co-variates. Strabismus was found to be significantly associated with a decrease in BiS at all three noise levels.
 
Keywords: 722 strabismus • 434 binocular vision/stereopsis  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×