April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Identification of Preferred Retinal Loci during Binocular Viewing in Patients with Central Vision Loss
Author Affiliations & Notes
  • Luminita Tarita-Nistor
    Vision Science Research Program, Toronto Western Hospital, Toronto, ON, Canada
    Centre for Vision Research, York University, Toronto, ON, Canada
  • Esther G Gonzalez
    Vision Science Research Program, Toronto Western Hospital, Toronto, ON, Canada
    Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
  • Moshe Eizenman
    Vision Science Research Program, Toronto Western Hospital, Toronto, ON, Canada
    Biomedical Engineering, University of Toronto, Toronto, ON, Canada
  • Natalie Landon-Brace
    Engineering Science, University of Toronto, Toronto, ON, Canada
  • Samuel N Markowitz
    Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
  • Martin J Steinbach
    Vision Science Research Program, Toronto Western Hospital, Toronto, ON, Canada
    Centre for Vision Research, York University, Toronto, ON, Canada
  • Footnotes
    Commercial Relationships Luminita Tarita-Nistor, None; Esther Gonzalez, None; Moshe Eizenman, El-MAR Inc. Toronto (P); Natalie Landon-Brace, None; Samuel Markowitz, None; Martin Steinbach, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4136. doi:
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      Luminita Tarita-Nistor, Esther G Gonzalez, Moshe Eizenman, Natalie Landon-Brace, Samuel N Markowitz, Martin J Steinbach; Identification of Preferred Retinal Loci during Binocular Viewing in Patients with Central Vision Loss. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4136.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Until now, the absolute location of the PRL of patients with central vision loss could only be identified monocularly. We tested a new method to measure/predict the location of the PRL in each eye in patients with central vision loss when viewing binocularly. The method uses a unique remote eye-tracking system that estimates the optical axes of both eyes without user calibration. We hypothesized that this method predicts the locations of monocular and binocular PRLs accurately.

Methods: Five experienced controls and 6 patients with stable central vision loss were tested. Their fixation was recorded monocularly with both the MP-1 microperimeter and the eye-tracking system and binocularly with the eye-tracking system. The eye-tracker measured the direction of the optical axis and the angle between the PRL (fovea for control subjects) and the optical axis in each eye. The MP-1 measured the location of the PRL relative to the optic disk; that is, its absolute location. Using the monocular measurements of the eye-tracker and the MP-1, in control subjects, a transformation from eye-tracking measurements to MP-1 measurements was created and used to predict the absolute location of the PRLs in patients. The predicted values for monocular viewing for each eye were compared with the measured MP-1 values.

Results: The prediction errors of the horizontal and vertical coordinates were -0.1 ± 0.7 deg and -0.1 ± 1.1 deg for the right eye, and -0.1 ± 0.9 deg and 0.0 ± 1.0 deg for the left eye. The same transformation was then used with measurements of the eye-tracker’s PRLs under binocular viewing, to obtain the absolute locations of the PRLs in the MP-1 coordinate system.

Conclusions: By transforming the measurements of the PRL location from an eye tracking coordinate system to the MP-1 coordinate system, the absolute location of the PRLs (i.e., relative to the optic disk) during binocular viewing can be predicted with an acceptable accuracy.

Keywords: 412 age-related macular degeneration • 584 low vision • 524 eye movements: recording techniques  
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