April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Relationship Between Ocular Pulse Amplitude, Scleral Rigidity And Axial Length In Patients With Arterial Hypertension And Primary Open Angle Glaucoma
Author Affiliations & Notes
  • Hissa Tavares-Gradvohl
    Ophthalmology, University of São Paulo, Fortaleza, Brazil
  • Jayter Silva Paula
    Ophthalmology, University of São Paulo, Fortaleza, Brazil
  • Ana Paula Paula
    Ophthalmology, University of São Paulo, Fortaleza, Brazil
  • Maria Lourdes Veronese Rodrigues
    Ophthalmology, University of São Paulo, Fortaleza, Brazil
  • Footnotes
    Commercial Relationships Hissa Tavares-Gradvohl, None; Jayter Paula, Allergan (F); Ana Paula Paula, None; Maria Rodrigues, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4260. doi:
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      Hissa Tavares-Gradvohl, Jayter Silva Paula, Ana Paula Paula, Maria Lourdes Veronese Rodrigues, ; Relationship Between Ocular Pulse Amplitude, Scleral Rigidity And Axial Length In Patients With Arterial Hypertension And Primary Open Angle Glaucoma. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4260.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Several mechanical factors, beyond intraocular pressure (IOP), have been described as contributors to glaucoma progression. The aim of this study is to investigate whether ocular pulse amplitude (OPA) and IOP are correlated with scleral rigidity (SR) and axial length (AL) in medically treated eyes of patients with both arterial hypertension and primary open angle glaucoma.

Methods: Ninety eyes of 90 adult glaucomatous subjects with arterial hypertension controlled with drugs were randomly evaluated. Dynamic contour tonometer (DCT, Pascal®) was used to determine OPA and IOP. IOP was also measured with Goldmann applanation and Schiotz tonometers and these measurements were used to calculate SR. The relationship between mean OPA with AL and SR was evaluated through linear regression analysis and correlation tests.

Results: Mean (±SD) values of DCT, OPA, SR and AL observed were 12.64±3.52 mmHg, 2.12±0.89 mmHg, 0.018±0.008 (arbitrary unit) and 23.34±1.62 mm, respectively. Spearman correlation tests showed significant correlation between both SR and OPA (r= -0.33, P=0.0013) and between SR and DCT readings (r=-0.27, P=0.0103). No significant correlation was observed between other parameters evaluated.

Conclusions: Based on our results, OPA and IOP readings measured with DCT were inversely related to SR. Although those parameters did not correlate with AL, mechanical factors attributed to cornea and sclera may interfere with IOP dynamics and should be further studied in several clinical conditions of normal and glaucomatous eyes.

Keywords: 628 optic flow • 708 sclera  
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