April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Volumetric Assessment of the Cornea, Anterior Chamber and Iris using Swept-Source Optical Coherence Topography in Pigment Dispersion Syndrome and Normal eyes
Author Affiliations & Notes
  • Christopher C Teng
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
    Ophthalmology, NYU School of Medicine, New York, NY
  • Ruojin Ren
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
  • Mugen Liu
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
  • Gustavo V De Moraes
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
    Ophthalmology, NYU School of Medicine, New York, NY
  • Lam Lu
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
  • Sung Chul Park
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
    Ophthalmology, New York Medical College, New York, NY
  • Jeffrey M Liebmann
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
    Ophthalmology, NYU School of Medicine, New York, NY
  • Robert Ritch
    Ophthalmology, Moise and Chella Safra Advanced Ocular Imaging Laboratory, Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY
    Ophthalmology, New York Medical College, New York, NY
  • Footnotes
    Commercial Relationships Christopher Teng, None; Ruojin Ren, None; Mugen Liu, None; Gustavo De Moraes, None; Lam Lu, None; Sung Chul Park, None; Jeffrey Liebmann, Alcon, Inc. (C), Allergan, Inc. (C), Bausch & Lomb, Inc. (C), Carl Zeiss Meditech, Inc. (C), Diopysis, Inc. (C), Heidelberg Engineering, GmbH (C), Merz Phamaceuticals, Inc. (C), National Institutes of Health (F), New York Glaucoma Research Institute (F), Optovue, Inc. (C), Quark Pharmaceuticals, Inc. (C), Reichert, Inc. (C), Sensimed, Inc. (C), Topcon, Inc. (C), Valeant Pharmaceutiicals, Inc. (C); Robert Ritch, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4280. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Christopher C Teng, Ruojin Ren, Mugen Liu, Gustavo V De Moraes, Lam Lu, Sung Chul Park, Jeffrey M Liebmann, Robert Ritch; Volumetric Assessment of the Cornea, Anterior Chamber and Iris using Swept-Source Optical Coherence Topography in Pigment Dispersion Syndrome and Normal eyes. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4280.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To compare cornea, anterior chamber and iris volumes between normal and pigment dispersion syndrome (PDS) eyes using swept-source optical coherence tomography (SS-OCT).

Methods: Volumetric radial scans of the cornea, anterior chamber and iris were performed using SS-OCT (Casia SS-1000; Tomey, Nagoya, Japan) in ambient light. Total, superior, inferior, nasal, and temporal quadrant volumes (mm3) were calculated for the cornea, anterior chamber, and iris in normal and pigment dispersion syndrome eyes, using the built-in software.

Results: 20 PDS eyes (10 patients; mean age, 42.6±11.7 years) and 16 normal eyes (11 patients; mean age, 38.4±12.0 years) were included. Compared to normal eyes, PDS eyes had greater total cornea volume (147.7±10.1 vs 133.5±11.3, p <0.01) and greater total anterior chamber volume (239.5±28.9 vs 179.3±35.1, p<0.01). There was no difference in total iris volume (44.4±4.7 vs 45.1±4.5, p=0.67) between the two groups. In PDS eyes, the superior quadrant cornea volume (34.0) (mm3) was less than the nasal (36.7), temporal (37.5) and inferior (39.5) quadrant volumes (p<0.01); but there was no difference in the anterior chamber volume (p=0.5) and iris volume (p=0.06) between the four quadrants. In normal eyes, the superior quadrant cornea volume (29.6) (mm3) was less than the nasal (33.9), temporal (35.3) and inferior (35.2) quadrant volumes (p<0.01); the superior quadrant anterior chamber volume (41.5) was also less than the nasal (42.8), temporal (46.8), and inferior (48.2) quadrant volumes, (p=0.04); and the superior iris volume (11.7) was greater than the nasal (10.8), temporal (11.2) and inferior (11.4) quadrant volumes (p=0.05).

Conclusions: Cornea and anterior chamber volumes are greater in PDS eyes compared to normal eyes. Differences in anterior chamber and iris volume may become less pronounced in PDS. Imaging the cornea, anterior chamber and iris using SS-OCT may be beneficial to help better understand the pathophysiology of PDS.

Keywords: 463 clinical (human) or epidemiologic studies: prevalence/incidence • 420 anterior chamber • 421 anterior segment  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×