April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Scotopic Contrast Sensitivity in Diabetic Patients with No Diabetic Retinopathy
Author Affiliations & Notes
  • Sare Safi
    Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Hamid Ahmadieh
    Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Anoushiravan Rahimi
    Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Eduardo C Solessio
    SUNY Eye Institute, Departments of Ophthalmology, Neuroscience and Physiology, and Center for Vision Research, Upstate Medical University, Syracuse, NY
  • Afsaneh Raeesi
    Department of Optometry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Hamid Safi
    Department of Ophthalmology, Shahid Sadoughi University of Medical Sciences, Yazd, Islamic Republic of Iran
  • Mohammad Haeri
    SUNY Eye Institute, Departments of Ophthalmology, Neuroscience and Physiology, and Center for Vision Research, Upstate Medical University, Syracuse, NY
  • Mohammad Aghazadeh Amiri
    Department of Optometry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Mojtaba Malek
    Endocrine Research Center (Firouzgar), Iran University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Mehdi Yaseri
    Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
  • Footnotes
    Commercial Relationships Sare Safi, None; Hamid Ahmadieh, None; Anoushiravan Rahimi, None; Eduardo Solessio, None; Afsaneh Raeesi, None; Hamid Safi, None; Mohammad Haeri, None; Mohammad Aghazadeh Amiri, None; Mojtaba Malek, None; Mehdi Yaseri, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4415. doi:
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    • Get Citation

      Sare Safi, Hamid Ahmadieh, Anoushiravan Rahimi, Eduardo C Solessio, Afsaneh Raeesi, Hamid Safi, Mohammad Haeri, Mohammad Aghazadeh Amiri, Mojtaba Malek, Mehdi Yaseri; Scotopic Contrast Sensitivity in Diabetic Patients with No Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4415.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To evaluate scotopic contrast sensitivity (CS) in diabetics with no diabetic retinopathy (DR) in comparison to normal subjects.

 
Methods
 

In this prospective comparative cross-sectional study, 46 diabetic patients with the mean age of 48±6 (range: 28 to 55) years were enrolled. All patients had the best corrected visual acuity (BCVA) of 20/20, no sign of diabetic retinopathy, and no macular involvement. CS was performed by using the CSV-1000 (Vector vision Inc.) instrument at four spatial frequencies (3, 6, 12, 18 cycles per degree) under scotopic (less than 2 lux) condition. The diabetics were compared with 46 normal healthy controls with no history of diabetes matched by their age and sex.

 
Results
 

In diabetic subjects, the mean and standard deviation of scotopic CS were 1.53±0.2, 1.8±0.22, 1.38±0.3 and 0.96±0.33 (log units) at 3, 6, 12 and 18 cycles per degree respectively. Corresponding values were 1.68±0.19, 1.93±0.25, 1.60±0.25 and 1.18±0.30 in controls (P<0.001) (Figure 1). After adjustment for age, significant reduction in CS was discovered only among diabetics with the age of 45 years or higher (P<0.001).

 
Conclusions
 

Significant reduction of scotopic CS occurs in diabetics before any sign of clinically detectable DR and the reduction is more prominent in older ages.

 
 
Figure 1. Mean scotopic CS in diabetics and control groups
 
Figure 1. Mean scotopic CS in diabetics and control groups
 
Keywords: 499 diabetic retinopathy • 478 contrast sensitivity  
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