Purchase this article with an account.
Sare Safi, Hamid Ahmadieh, Anoushiravan Rahimi, Eduardo C Solessio, Afsaneh Raeesi, Hamid Safi, Mohammad Haeri, Mohammad Aghazadeh Amiri, Mojtaba Malek, Mehdi Yaseri; Scotopic Contrast Sensitivity in Diabetic Patients with No Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4415.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To evaluate scotopic contrast sensitivity (CS) in diabetics with no diabetic retinopathy (DR) in comparison to normal subjects.
In this prospective comparative cross-sectional study, 46 diabetic patients with the mean age of 48±6 (range: 28 to 55) years were enrolled. All patients had the best corrected visual acuity (BCVA) of 20/20, no sign of diabetic retinopathy, and no macular involvement. CS was performed by using the CSV-1000 (Vector vision Inc.) instrument at four spatial frequencies (3, 6, 12, 18 cycles per degree) under scotopic (less than 2 lux) condition. The diabetics were compared with 46 normal healthy controls with no history of diabetes matched by their age and sex.
In diabetic subjects, the mean and standard deviation of scotopic CS were 1.53±0.2, 1.8±0.22, 1.38±0.3 and 0.96±0.33 (log units) at 3, 6, 12 and 18 cycles per degree respectively. Corresponding values were 1.68±0.19, 1.93±0.25, 1.60±0.25 and 1.18±0.30 in controls (P<0.001) (Figure 1). After adjustment for age, significant reduction in CS was discovered only among diabetics with the age of 45 years or higher (P<0.001).
Significant reduction of scotopic CS occurs in diabetics before any sign of clinically detectable DR and the reduction is more prominent in older ages.
This PDF is available to Subscribers Only