April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Prevalence of HPV in conjunctiva of healthy subjects in Mexican population
Author Affiliations & Notes
  • Hector Javier Perez-Cano
    Centro de Investigación Biomédica, Hospital Foundation "Nuestra Señora de la Luz", Mexico City, Mexico
  • Ezequiel G Díaz-Benítez
    Orbita, Párpados y Vías Lagrimales, Hospital Foundation "Nuestra Señora de la Luz", Mexico City, Mexico
  • Miriam G Rojas-Tejeda
    Orbita, Párpados y Vías Lagrimales, Hospital Foundation "Nuestra Señora de la Luz", Mexico City, Mexico
  • Footnotes
    Commercial Relationships Hector Perez-Cano, None; Ezequiel Díaz-Benítez, None; Miriam Rojas-Tejeda, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4449. doi:
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      Hector Javier Perez-Cano, Ezequiel G Díaz-Benítez, Miriam G Rojas-Tejeda, ; Prevalence of HPV in conjunctiva of healthy subjects in Mexican population. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4449.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Human papillomavirus (HPV) and their genotypes are widely distributed in the world. It has no seasonal incidence, it is one of the sexually transmitted infections more frequent and 16,18,31,33,35,39, 45, 51,52,56,58,59 and 66 genotypes, have been implicated in the development of cervical cancer. HPV has been linked in ocular diseases such as the development of pterygium and ocular surface squamous neoplasia. In this study we determine the presence of HPV in conjunctiva of healthy subjects.

Methods: We studied a group of 50 healthy subjects of both sexes over 18 years of age and without ocular pathology. 50 Samples of scraping conjunctival were studied. We perform DNA extraction. The presence of HPV by the technique of the polymerase chain reaction was determined using universal oligonucleotides MY09/MY11. The positive samples were genotyped by terminators fluorescent nucleotide sequencing.

Results: We obtained. 50 samples (27 men and 23 women) aged between 20 and 51 years. The samples analyzed by PCR for the detection of HPV, 2 were positive; it corresponds to 2% of the population. The results grouped by gender corresponding to 3% of the male population and 4% of the female population

Conclusions: The prevalence of HPV found is similar to those reported in other countries. This study highlights the importance of focused preventive measurements to diseases caused by this virus, without forgetting the eye diseases.

Keywords: 631 orbit • 593 microbial pathogenesis: clinical studies • 459 clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology  
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