April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
En face spectral domain optical coherence tomography: a novel tool for anterior segment imaging
Author Affiliations & Notes
  • Rachid Tahiri Joutei Hassani
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    Clinical Investigation Center (CIC) INSERM 503, Quinze-Vingts National Ophthalmology Hospital, Paris, France
  • Hong Liang
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    Clinical Investigation Center (CIC) INSERM 503, Quinze-Vingts National Ophthalmology Hospital, Paris, France
  • Mohamed El Sanharawi
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
  • Emmanuelle Brasnu
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    Clinical Investigation Center (CIC) INSERM 503, Quinze-Vingts National Ophthalmology Hospital, Paris, France
  • Sofiene Kallel
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    Department of Ophthalmology,, Ambroise Paré Hospital, APHP, University of Versailles, Boulogne, France
  • Antoine Labbe
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    Department of Ophthalmology,, Ambroise Paré Hospital, APHP, University of Versailles, Boulogne, France
  • Christophe Baudouin
    Department III, XV XX National Ophthalmloogy Hospital, Paris, France
    INSERM U 968, UMR S 968, CNRS, UMR 7210, 45, Institut de la Vision, UMPC University Paris 06, Paris, France
  • Footnotes
    Commercial Relationships Rachid Tahiri Joutei Hassani, None; Hong Liang, None; Mohamed El Sanharawi, None; Emmanuelle Brasnu, None; Sofiene Kallel, None; Antoine Labbe, None; Christophe Baudouin, Alcon pharmaceuticals (F), Santen pharmaceuticals (F), Thea pharmaceuticals (F)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4869. doi:
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      Rachid Tahiri Joutei Hassani, Hong Liang, Mohamed El Sanharawi, Emmanuelle Brasnu, Sofiene Kallel, Antoine Labbe, Christophe Baudouin; En face spectral domain optical coherence tomography: a novel tool for anterior segment imaging. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4869.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To explore the potential of en face optical coherence tomography for the imaging of anterior segment diseases and to correlate the findings with conventional B-scans and in vivo confocal microscopy (IVCM) images.

 
Methods
 

In this observational case series, 140 eyes of 90 subjects with various anterior diseases were investigated with anterior-segment en face spectral-domain OCT between January and June 2013. The correlations between en face OCT images, biomicroscopy, conventional B-scans and IVCM were analyzed.

 
Results
 

The diseases evaluated included pterygium, conjunctivochalasis, corneal deposits, dry eye keratitis, peripheral sterile infiltrates and infectious keratitis. En face OCT images showed anterior segment changes that were not discernible using conventional B-scans OCT. There was a good correlation with IVCM analysis. Compared with IVCM, the major advantages of en-face OCT included easy operation and rapid image acquisition, with minimal experience required. In addition, the non-contact method prevented patient discomfort and external pressure on the globe, which was especially useful in patients with corneal ulcers or infectious keratitis. Although the resolution of en-face OCT was lower than that of IVCM, it allowed useful overall visualization of corneal lesions due to the larger areas analyzed.

 
Conclusions
 

En-face SD-OCT is a novel, interesting tool to assess a wide variety of anterior segment conditions. Without corneal contact, it can provide additional information and new insight into different ocular surface conditions. With continued improvements in its technology, future development of en-face ultra-high-resolution (UHR) OCT will certainly improve resolution and enhance the sensitivity and specificity of this new technology, allowing earlier diagnosis and more reliable follow-up.

 
 
A: Intraconjunctival network in atypical conjunctivochalasis B: Subconjunctival fibrosis in chronic conjunctivochalasis C: Herpetic epithelial keratitis D: Infectious keratitis E: Pterygium F: radial keratotomy
 
A: Intraconjunctival network in atypical conjunctivochalasis B: Subconjunctival fibrosis in chronic conjunctivochalasis C: Herpetic epithelial keratitis D: Infectious keratitis E: Pterygium F: radial keratotomy
 
Keywords: 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 550 imaging/image analysis: clinical  
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