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Janet L Leasher, Jost B Jonas, Rupert Bourne, Seth R Flaxman, Jill Keeffe, Kovin Shunmugam Naidoo, Konrad Pesudovs, Tien Y Wong, Serge Resnikoff, Hugh R Taylor, Vision Loss Expert Group of the Global Burden of Disease Study 2010; Number of People Blind or Visually Impaired by Diabetic Retinopathy Worldwide and in World Regions 1990 - 2010. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5366.
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© ARVO (1962-2015); The Authors (2016-present)
To estimate the number of people visually impaired or blind due to diabetic retinopathy (DR).
Based on the Global Burden of Disease GBD) Study 2010 and ongoing literature searches to January 2012, we estimated trends in causes of moderate and severe vision impairment (MSVI; presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60).
In 2010, out of overall 32.4 million blind and 191 million vision impaired, 834,000 (95% uncertainty interval (UI): 703,000, 1,102,000) people were blind, and 3.7 million (95% uncertainty interval (UI):3.1,5.5) were visually impaired due to DR. From 1990 to 2010, the number of blind or visually impaired due to DR increased by 176,000 (95%UI: 136,000, 535,000) or 27% and by 1.445 million (95%UI: 1,289, 2,561) or 64%, respectively. DR caused worldwide 2.6% (95%UI: 2.2,3.4) of all blindness in 2010 and 1.9% (95%UI: 1.6,2.7) of all MSVI. These figures were lower in regions with younger populations (<2% in East and Southeast Asia, Oceania) than in high-income regions with relatively older populations (>4%). From 1990 to 2010, the figures increased from 2.1% (1.9,2.5) to 2.6%, and from 1.3% (1.2,1.6) to 1.9%, respectively. This took place in all world regions except in Western Europe and high-income North America where a slight decrease occurred. The age-standardized prevalence of DR related blindness and MSVI in adults aged 50+ years were higher in women than in men 0.1% (95%UI:0.0,0.1) versus 0.0% (95%UI:0.0,0.1); and 0.2% (95%UI:0.2,0.4) versus 0.2% (95%UI:0.1,0.3), respectively. Both values were highest in North Africa/Middle East (0.6%;95%UI: 0.4,0.9 and 1.0%;95%UI: 0.7,1.16, respectively) and all regions of Sub-Saharan Africa and lowest in high-income regions and South Asia. Both prevalences increased from 1990 to 2010 in all Sub-Saharan regions (from 0.18% to 0.45% for blindness; from 0.3% to 0.8% for MSVI) and did not change in the other regions.
In 2010, 0.8 million people were blind and 3.7 million people were visually impaired due to DR, with an increase by 176,000 (27%) and 1.4 million (64%) from 1990 to 2010. Age-standardized prevalence of DR related blindness and MSVI was higher in women and in Sub-Saharan Africa. One out of 39 blind people was blind due to DR, and one out of 52 visually impaired people was visually impaired due to DR.
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