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Daniel Sand, David Chen, Mathew Schur, Ira A Shulman, Hugo Y Hsu; Microbial Keratitis. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5469.
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To evaluate the spectrum and antibiotic susceptibility panel of infectious keratitis at a major county hospital in Southern California.
IRB approved retrospective review of infectious keratitis cases from 7/1/08 to 12/31/12.
172 cases were identified. 151 cases (88%) had a positive yield and 92 cases (61%) were monomicrobial. 217 organisms were identified of which 43 were unique. Coagulase-negative Staphylococci was the most commonly identified Gram-positive bacteria and Pseudomonas aeruginosa was the most commonly identified Gram-negative bacteria. 58% of all isolates were resistant to fluoroquinolones and 48% were resistant to gentamicin. 47% of Staphylococcus aureus were ORSA.
Our series revealed that Gram-positive bacteria were the most common pathogen in infectious keratitis cases at our county hospital in Southern California with 42% of all isolates being sensitive to fluoroquinolones.
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