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vanessa valderrama, Miguel Pedroza-Seres; Vogt Koyanagi Harada disease in pediatric patients. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5800.
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To determine incidence rates of Vogt Koyanagi Harada disease in pediatric patients, because it is a very rare disease in this group.
Clinical files were reviewed of all patients from the consultation of Department of Uveitis e Inmunologia Ocular of Instituto de Oftalmologia Fundacion Conde de Valenciana, in Mexico City, from november 2007, to february 2013, with diagnostic of Vogt Koyanagi Harada. We selected only patients younger than 18 years.
A total of 135 patients with diagnosis Vogt Koyanagi Harada disease were reviewed in our study period, from this group, 8 patients (5.9%) were younger than 18 years, with an average age of 15.6 years, with the younger age of presentation of 9 years, from which 2 patients were males, 6 were females. Initial clinical manifestation was in 100% of cases bilateral serous retinal detachment. All of the patients reported headache (2 of them were treated by neurologist as migraine). Two patients presented with recurrences at 8 months and 1 year from the acute phase. Only one patient had vitiligo. the sister one patient has had Vogt Koyanagi Harada, initiating at the age of 20 years. The most frequent complication were cataracts in 4 patients (50%), ocular hypertension in 2 patients (25%), and subretinal fibrosis in 2 patients (25%).
Clinical presentation of Vogt Koyanagi Harada disease is similar to the one described in the literature for adults. In our case series, 100% of the children presented themselves initially with the incomplete form of this disease. Vogt Koyanagi Harada in our institution, represent 5.7% of the total number of uveitis being found, with a 5.9% corresponding to pediatric patients with Vogt Koyanagi Harada. Visual recovery of this pediatric patients was of LogMAR 0.18 in 75% of cases. Only one children presented the complete form of the disease during the 5 years follow up.
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