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Atsushi Fujiwara, Chieko Shiragami, Saki Manabe, Saeko Izumibata, Akiko Murata, Yuki Morizane, Fumio Shiraga; Normal values of retinal sensitivity determined by Macular Integrity Assessment. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5875.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the macular sensitivity of healthy eyes with wide age range determined by macular Integrity Assessment (MAIA), and investigated factors affect to the macular sensitivity.
A total of 120 eyes of 120 healthy volunteers (65 females, 55 males) and a best-corrected visual acuity of 20/20 or better, mean age, 43.1±21.9 years (age range, 7-79 years). These subjects had to have a spherical equivalent refractive error between +3.75 D and -6.50 D. The macular sensitivity examined by a Standard Grid, a 37-stimuli grid covering the central 10°of the retina which included one centering point.
The central sensitivity (CS) was 28.9±1.5 dB for subjects under 20 years, 27.2±2.4 dB for subjects between 20 to 60 years, 24.5±2.1 dB for subjects over 60 years, the average sensitivity (AS) was 29.6±1.8 dB for subjects under 20 years, after that a sensitivity was 28.7±1.4 dB, 26.3±2.9 dB, both CS and AS in subjects over 60 years exhibited a significantly lower than those under the age of 20 (p=0.01), and regression analysis results indicated that the sensitivity gradually decreased by approximately 0.6 dB every 10 years (p=0.01). The age and development of axial length were statistically significant factors to influence of decline in the sensitivity (p=0.01).
The macular sensitivity in Japanese health subjects calculated by MAIA exhibited a significantly low value with aging, and sensitivity decreases with the advance of development of axial length.
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