April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Vitreoretinal interface disorders assessed by SD-OCT in patients with retinopathy of prematurity
Author Affiliations & Notes
  • Sarai Delgado-Pelayo
    Retina, Asociación para Evitar la Ceguera, México, Mexico
  • Victoria González
    Retina, Asociación para Evitar la Ceguera, México, Mexico
  • Veronica Evangelina Giordano
    Retina, Asociación para Evitar la Ceguera, México, Mexico
  • Maria Ana Martinez-Castellanos
    Retina, Asociación para Evitar la Ceguera, México, Mexico
  • Footnotes
    Commercial Relationships Sarai Delgado-Pelayo, None; Victoria González, None; Veronica Giordano, None; Maria Martinez-Castellanos, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 5931. doi:
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      Sarai Delgado-Pelayo, Victoria González, Veronica Evangelina Giordano, Maria Ana Martinez-Castellanos, ; Vitreoretinal interface disorders assessed by SD-OCT in patients with retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5931.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

In patients born prematurely, characteristic retinal and vitreous pathological conditions place these patients at increased risk for retinal complications throughout their lives. In this study, we describe the vitreorretinal interface disorders in patients with retinopathy of prematurty (ROP).

 
Methods
 

A descriptive and retrospective study of 43 patients with retinopathy of prematurity were examined with a handheld spectral domain optical coherence tomography (SD- OCT), during the period from January 2012 to November 2013. The changes were analyzed by two different observers.

 
Results
 

The records of 43 patients were obtained with a diagnosis of ROP, male: 67%, female: 33%, with gestational age in the range of 26 to 34 weeks (mean 30.1 ±2.5) and birth weight of range 700 to 1580 grams (mean 1145 grams ±208.7). It was possible to perform the analysis of 74 eyes with ROP diagnosis through images with SD-OCT, in which were observed in 46% thickening of the internal limiting membrane, 15% presented detached hyaloid, 12% thickened hyaloid, 3% with evidence of tractional retinoschisis and 3% demarcation line vitreoretinal changes with a hypereflectic tissue that grows from middle and outer retinal layers that folds on the surface. Apparent cystic spaces located between the tissue and the internal limiting membrane that corresponds to the demarcation line at the equator. All patients were classified according to: zone 1 (14 %); zone 2 (61%); zone 3 (22%); aggressive posterior ROP (4%); stage I (28%); stage 2 (55%); stage III (12%) and stage IV (3%).

 
Conclusions
 

Optical coherence tomography is useful to identify specific changes at the vitreoretinal interface in patients with ROP. More studies must to be performed for define these changes accurately and correlate with clinical finding though time thus providing new classifications of the pathology.

 
 
Hypereflectic tissue that grows from middle and outer retinal layers that folds on the surface, corresponds to the demarcation line at the equator.
 
Hypereflectic tissue that grows from middle and outer retinal layers that folds on the surface, corresponds to the demarcation line at the equator.
 
Keywords: 706 retinopathy of prematurity • 496 detection • 698 retinal development  
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