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Yasuki Ito, Ruka Maruko, Yosuke Nagasaka, Kazuhiro Oiwa, Hiroko Terasaki; Subfoveal choroidal thickness of smoking and non-smoking patients with central serous chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):6389.
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© ARVO (1962-2015); The Authors (2016-present)
The subfoveal choroidal thickness in eyes with central serous chorioretinopathy (CSC) was reported to be thicker. The purpose of this study is to identify the parameters which are associated with subfoveal choroidal thickness in eyes with CSC. The association between subfoveal choroidal thickness and current smoking habit was also evaluated.
Forty eyes of 40 patients (7 women and 33 men, age: 48.9 ± 8.9 years) of chronic CSC were retrospectively studied. Subfoveal choroidal thickness was measured with spectral domain optical coherence tomography (SD-OCT) and compared between smokers and non-smokers. The multivariate analysis was also performed with subfoveal choroidal thickness as the dependent variable, the axial length, age, sex, and current smoking habit as the independent variable, to find the parameters associated with subfoveal choroidal thickness in eyes with CSC.
Overall mean ± average subfoveal choroidal thickness was 422.4 ± 98.0 µm. Among 40 patients, there were 18 smokers and 22 non-smokers. Subfoveal choroidal thickness in current smokers was 454.8 ± 101.3µm and significantly thicker than 393.7 ± 19.7 µm in non-smokers (p<0.05). Multivariate analysis showed that current smoking habit was the only parameter associated with subfoveal choroidal thickness (p<0.05).
Current smoking habit is associated with thicker subfoveal choroidal thickness in eyes with CSC. Although current smoking habit was not reported to be the distinct risk factor of CSC, current smoking habit may be the factor that worsen the CSC.
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